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A 2014 literature review identified seven small randomized controlled trials examining the effect of coenzyme Q 10 supplementation (60-200 mg/day for 3 months in most trials) in heart failure patients (33)

4.3 Synergistic integration of gene editing and network pharmacology in driving precision anti-inflammatory therapy and systems-level optimization Contemporary strategies in anti-inflammatory drug development are transitioning from empirical approaches toward precision-targeted and system-level regulatory interventions

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Gen Comp Endocrinol (2010) 167:34451